For Acid Reflux & Upper GI Motility Disorders
℞ - Pantoprazole Gastro-resistant and Domperidone Prolonged-release Capsules IP
Pantopax® DSR is a dual-action formulation combining Pantoprazole, a proton pump inhibitor, with prolonged-release Domperidone, a prokinetic agent. It provides effective gastric acid suppression while improving gastrointestinal motility, offering comprehensive relief in GERD and reflux conditions associated with delayed gastric emptying.
- Gastroesophageal reflux disease (GERD)
- Acid reflux associated with nausea and vomiting
- Functional dyspepsia
- Delayed gastric emptying
- Reflux symptoms associated with bloating and fullness
Pantopax® DSR is designed to address both the acid component and the motility dysfunction underlying reflux disorders. By combining sustained acid suppression with enhanced gastric emptying, it helps reduce reflux symptoms such as heartburn, regurgitation, nausea, bloating, and post-meal fullness.
Why Pantopax® DSR
◉ Dual mechanism addressing acid secretion and reflux physiology
◉ Prolonged-release domperidone ensures sustained prokinetic action
◉ Helps reduce recurrence of reflux symptoms linked to dysmotility
◉ Particularly suitable for GERD patients with bloating, nausea, and fullness
◉ Once-daily dosing improves patient adherence
Mechanism of Action
Pantopax® DSR combines acid suppression with motility enhancement:
◉ Pantoprazole
Irreversibly inhibits the gastric H⁺/K⁺-ATPase (proton pump), reducing both basal and stimulated gastric acid secretion.
◉ Domperidone (Prolonged-release)
Enhances gastrointestinal motility and accelerates gastric emptying through peripheral dopamine D₂-receptor antagonism.
Key Clinical Advantages
◉ Comprehensive management of acid reflux and dysmotility
◉ Sustained acid suppression with improved gastric emptying
◉ Prolonged-release formulation ensures longer therapeutic effect
◉ Reduces recurrence of reflux symptoms
◉ Suitable for GERD patients with associated upper GI motility disorders
◉ Once-daily dosing for better compliance
Dosage & Administration
Dosage:
As directed by the physician.
Administration:
Preferably taken after meals.
Schedule H Prescription Drug – Caution
Not to be sold by retail without the prescription of a Registered Medical Practitioner.
